Hi all, Tomorrow Adrian will talk at group meeting (note the nonstandard time). See below for the title and abstract! Best, Ian ----------------- Title: Exploring Redox Metabolism with Electrochemistry Adrian Jinich Abstract: The original speaker for this group meeting cancelled so I am substituting for him/her. I will talk about a topic that evolved from a (not-so) crazy idea, i.e. cross-pollination of two subfields in the AAG lab: Redox Metabolism + Redox Flow Batteries. The basic idea is whether we can use techniques from electrochemistry to experimentally measure the thermodynamic (and other!) parameters of metabolic redox reactions that we’ve been working so hard on getting from quantum chemical simulations. Cyclic Voltammetry (CV) seems to be the technique of choice, and I will discuss the basics and the complications that arise from setting up a metabolic redox reaction in a CV experiment. I will discuss some ideas (thanks to Florian Hase) on how to obtain the parameters of interest from the CV curves using a mixture of Bayesian Optimization and stochastic simulation with the Gillespie Algorithm.