Dear Group,
The Theory Seminar on Tue 9 Dec will meet in Naito 030 (Zhuang conference
room) instead of Naito 307. I will send another reminder on Tue 9 Dec.
Thank you!
Anna
On Wed, Dec 3, 2008 at 10:49 AM, Anna B. Shin <anna(a)chemistry.harvard.edu>wrote;wrote:
Dear Group,
Dr. Jingzhi Pu of the Karplus Group will present the second Joint Theory
Seminar on Tue 9 Dec at 4:15pm in the Kishi Conference Room (Naito 307 near
the Bauer side of Naito). Dr. Pu's title and abstract are as follows:
*Coupling Mechanisms in F1-ATPase*
*F1-ATPase is the smallest rotary motor in biology. With ATP binding,
hydrolysis, and product release, the motor induces a torque on the central
shaft gamma-subunit, which rotates about 1000/sec in one direction. When an
applied torque rotates the gamma-subunit in the reverse direction, the motor
synthesizes ATP, its normal function in living cells. In this presentation,
we will discuss the progress of using a multiscale approach that combines
coarse-grained model, targeted molecular dynamics and free energy
simulations to elucidate how the rotary motion is achieved via intimate
coupling between the ligand binding/catalytic subunit conformations and the
gamma-subunit.*
Our next seminar will be presented by Roberto in January. An announcement
will be sent early next month.
Best,
Anna
--
Anna B. Shin
Aspuru-Guzik Group Administrator
Department of Chemistry and Chemical Biology
Harvard University
12 Oxford Street
Cambridge, MA 02138
617.496.9964 phone
617.496.9411 fax
anna(a)chemistry.harvard.edu
Aspuru-Guzik Group URL:
http://aspuru.chem.harvard.edu/
--
Anna B. Shin
Aspuru-Guzik Group Administrator
Department of Chemistry and Chemical Biology
Harvard University
12 Oxford Street
Cambridge, MA 02138
617.496.9964 phone
617.496.9411 fax
anna(a)chemistry.harvard.edu
Aspuru-Guzik Group URL:
http://aspuru.chem.harvard.edu/